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Structural basis of homologous recombination
Homologous recombination (HR) is a pathway to faithfully repair DNA double-strand breaks (DSBs). At the core of this pathway is a DNA recombinase, which, as a nucleoprotein filament on ssDNA, pairs with homologous DNA as a template to repair the damaged site. In eukaryotes Rad51 is the recombinase c...
Autores principales: | Sun, Yueru, McCorvie, Thomas J., Yates, Luke A., Zhang, Xiaodong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957567/ https://www.ncbi.nlm.nih.gov/pubmed/31748913 http://dx.doi.org/10.1007/s00018-019-03365-1 |
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