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Noninvasive rapid detection of metabolic adaptation in activated human T lymphocytes by hyperpolarized (13)C magnetic resonance

The metabolic shift induced in human CD4(+) T lymphocytes by stimulation is characterized by an upregulation of glycolysis, leading to an augmentation in lactate production. This adaptation has already been highlighted with various techniques and reported in several previous studies. We herein propo...

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Detalles Bibliográficos
Autores principales: Can, Emine, Mishkovsky, Mor, Yoshihara, Hikari A. I., Kunz, Nicolas, Couturier, Dominique-Laurent, Petrausch, Ulf, Doucey, Marie-Agnès, Comment, Arnaud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957688/
https://www.ncbi.nlm.nih.gov/pubmed/31932697
http://dx.doi.org/10.1038/s41598-019-57026-1