Cargando…
Noninvasive rapid detection of metabolic adaptation in activated human T lymphocytes by hyperpolarized (13)C magnetic resonance
The metabolic shift induced in human CD4(+) T lymphocytes by stimulation is characterized by an upregulation of glycolysis, leading to an augmentation in lactate production. This adaptation has already been highlighted with various techniques and reported in several previous studies. We herein propo...
Autores principales: | Can, Emine, Mishkovsky, Mor, Yoshihara, Hikari A. I., Kunz, Nicolas, Couturier, Dominique-Laurent, Petrausch, Ulf, Doucey, Marie-Agnès, Comment, Arnaud |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957688/ https://www.ncbi.nlm.nih.gov/pubmed/31932697 http://dx.doi.org/10.1038/s41598-019-57026-1 |
Ejemplares similares
-
[(13)C]bicarbonate labelled from hyperpolarized [1-(13)C]pyruvate is an in vivo marker of hepatic gluconeogenesis in fasted state
por: Can, Emine, et al.
Publicado: (2022) -
Hyperpolarized (13)C Magnetic Resonance Spectroscopy
Reveals the Rate-Limiting Role of the Blood–Brain Barrier in
the Cerebral Uptake and Metabolism of l-Lactate in Vivo
por: Takado, Yuhei, et al.
Publicado: (2018) -
Measuring glucose cerebral metabolism in the healthy mouse using hyperpolarized (13)C magnetic resonance
por: Mishkovsky, Mor, et al.
Publicado: (2017) -
Hyperpolarized (13)C-glucose magnetic resonance highlights reduced aerobic glycolysis in vivo in infiltrative glioblastoma
por: Mishkovsky, Mor, et al.
Publicado: (2021) -
Assessment of Aspartate and Bicarbonate Produced From Hyperpolarized [1-(13)C]Pyruvate as Markers of Renal Gluconeogenesis
por: Yoshihara, Hikari A. I., et al.
Publicado: (2021)