The nuclear receptor FXR inhibits Glucagon-Like Peptide-1 secretion in response to microbiota-derived Short-Chain Fatty Acids

The gut microbiota participates in the control of energy homeostasis partly through fermentation of dietary fibers hence producing short-chain fatty acids (SCFAs), which in turn promote the secretion of the incretin Glucagon-Like Peptide-1 (GLP-1) by binding to the SCFA receptors FFAR2 and FFAR3 on...

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Detalles Bibliográficos
Autores principales: Ducastel, Sarah, Touche, Véronique, Trabelsi, Mohamed-Sami, Boulinguiez, Alexis, Butruille, Laura, Nawrot, Margaux, Peschard, Simon, Chávez-Talavera, Oscar, Dorchies, Emilie, Vallez, Emmanuelle, Annicotte, Jean-Sébastien, Lancel, Steve, Briand, Olivier, Bantubungi, Kadiombo, Caron, Sandrine, Bindels, Laure B., Delzenne, Nathalie M., Tailleux, Anne, Staels, Bart, Lestavel, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957696/
https://www.ncbi.nlm.nih.gov/pubmed/31932631
http://dx.doi.org/10.1038/s41598-019-56743-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957696/
https://www.ncbi.nlm.nih.gov/pubmed/31932631
http://dx.doi.org/10.1038/s41598-019-56743-x

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