UCP2-induced hypoxia promotes lipid accumulation and tubulointerstitial fibrosis during ischemic kidney injury

Mitochondrial dysfunction leads to loss of renal function and structure; however, the precise mechanisms by which mitochondrial function can regulate renal fibrosis remain unclear. Proximal tubular cells (PTCs) prefer fatty acid oxidation as their energy source and dysregulation of lipid metabolism...

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Detalles Bibliográficos
Autores principales: Ke, Qingqing, Yuan, Qi, Qin, Nan, Shi, Caifeng, Luo, Jing, Fang, Yi, Xu, Lingling, Sun, Qi, Zen, Ke, Jiang, Lei, Zhou, Yang, Yang, Junwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957698/
https://www.ncbi.nlm.nih.gov/pubmed/31932578
http://dx.doi.org/10.1038/s41419-019-2219-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957698/
https://www.ncbi.nlm.nih.gov/pubmed/31932578
http://dx.doi.org/10.1038/s41419-019-2219-4

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