Spatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation

Lysosomes are membrane-surrounded cytoplasmic organelles filled with a powerful cocktail of hydrolases. Besides degrading cellular constituents inside the lysosomal lumen, lysosomal hydrolases promote tissue remodeling when delivered to the extracellular space and cell death when released to the cyt...

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Detalles Bibliográficos
Autores principales: Hämälistö, Saara, Stahl, Jonathan Lucien, Favaro, Elena, Yang, Qing, Liu, Bin, Christoffersen, Line, Loos, Ben, Guasch Boldú, Claudia, Joyce, Johanna A., Reinheckel, Thomas, Barisic, Marin, Jäättelä, Marja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957743/
https://www.ncbi.nlm.nih.gov/pubmed/31932607
http://dx.doi.org/10.1038/s41467-019-14009-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957743/
https://www.ncbi.nlm.nih.gov/pubmed/31932607
http://dx.doi.org/10.1038/s41467-019-14009-0

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