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GSTpi regulates VE-cadherin stabilization through promoting S-glutathionylation of Src

GSTpi is a Phase II metabolic enzyme which is originally considered as an important facilitator of cellular detoxification. Here, we found that GSTpi stabilized VE-cadherin in endothelial cell membrane through inhibiting VE-cadherin phosphorylation and VE-cadherin/catenin complex dissociation, and c...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Dong, Xiaoliang, Zheng, Shuangning, Sun, Jinbing, Ye, Juan, Chen, Jiao, Fang, Yuan, Zhao, Bing, Yin, Zhimin, Cao, Peng, Luo, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957793/
https://www.ncbi.nlm.nih.gov/pubmed/31927409
http://dx.doi.org/10.1016/j.redox.2019.101416