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Persister Cells Resuscitate Using Membrane Sensors that Activate Chemotaxis, Lower cAMP Levels, and Revive Ribosomes

Persistence, the stress-tolerant state, is arguably the most vital phenotype since nearly all cells experience nutrient stress, which causes a sub-population to become dormant. However, how persister cells wake to reconstitute infections is not understood well. Here, using single-cell observations,...

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Detalles Bibliográficos
Autores principales: Yamasaki, Ryota, Song, Sooyeon, Benedik, Michael J., Wood, Thomas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957856/
https://www.ncbi.nlm.nih.gov/pubmed/31926430
http://dx.doi.org/10.1016/j.isci.2019.100792