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Bucillamine Prevents Afatinib-Mediated Inhibition of Epidermal Growth Factor Receptor Signaling

Molecular targeting therapies often cause characteristic adverse effects, such as skin rash during anti-epidermal growth factor receptor (EGFR) therapies, making treatment continuation difficult. In contrast, skin symptoms induced by EGFR inhibition are strongly correlated with the overall survival...

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Detalles Bibliográficos
Autores principales: Nishiya, Naoyuki, Murai, Moeka, Hosoda, Ayumi, Yonezawa, Honami, Omori, Norikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958386/
https://www.ncbi.nlm.nih.gov/pubmed/31703435
http://dx.doi.org/10.3390/ph12040165