Biological Evaluation of Arylsemicarbazone Derivatives as Potential Anticancer Agents

Fourteen arylsemicarbazone derivatives were synthesized and evaluated in order to find agents with potential anticancer activity. Cytotoxic screening was performed against K562, HL-60, MOLT-4, HEp-2, NCI-H292, HT-29 and MCF-7 tumor cell lines. Compounds 3c and 4a were active against the tested cance...

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Detalles Bibliográficos
Autores principales: Nascimento da Cruz, Anne Cecília, Brondani, Dalci José, I´talo de Santana, Temístocles, Oliveira da Silva, Lucas, da Oliveira Borba, Elizabeth Fernanda, de Faria, Antônio Rodolfo, Ferreira Cavalcanti de Albuquerque, Julianna, Piessard, Sylvie, Matos Ximenes, Rafael, Baratte, Blandine, Bach, Stéphane, Ruchaud, Sandrine, Bezerra Mendonça Junior, Francisco Jaime, Bazin, Marc-Antoine, Montenegro Rabello, Marcelo, Zaldini Hernandes, Marcelo, Marchand, Pascal, Gonçalves da Silva, Teresinha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958387/
https://www.ncbi.nlm.nih.gov/pubmed/31744203
http://dx.doi.org/10.3390/ph12040169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958387/
https://www.ncbi.nlm.nih.gov/pubmed/31744203
http://dx.doi.org/10.3390/ph12040169

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