In Vitro Characterization and Stability Profiles of Antibody–Fluorophore Conjugates Derived from Interchain Cysteine Cross-Linking or Lysine Bioconjugation

Fluorescent labelling of monoclonal antibodies (mAbs) is classically performed by chemical bioconjugation methods. The most frequent labelling technique to generate antibody–fluorophore conjugates (AFCs) involves the bioconjugation onto the mAb lysines of a dye bearing an N-hydroxysuccinimide ester...

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Detalles Bibliográficos
Autores principales: Martin, Camille, Brachet, Guillaume, Colas, Cyril, Allard-Vannier, Emilie, Kizlik-Masson, Claire, Esnault, Clara, Respaud, Renaud, Denevault-Sabourin, Caroline, Chourpa, Igor, Gouilleux-Gruart, Valérie, Viaud-Massuard, Marie-Claude, Joubert, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958397/
https://www.ncbi.nlm.nih.gov/pubmed/31810248
http://dx.doi.org/10.3390/ph12040176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958397/
https://www.ncbi.nlm.nih.gov/pubmed/31810248
http://dx.doi.org/10.3390/ph12040176

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