Reduced FXR Target Gene Expression in Copper-Laden Livers of COMMD1-Deficient Dogs

Wilson’s disease (WD), an autosomal recessive disorder, results in copper accumulation in the liver as a consequence of mutations in the gene ATPase copper transporting beta (ATP7B). The disease is characterized by chronic hepatitis, eventually resulting in liver cirrhosis. Recent studies have shown...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoyan, Chien, Hsiaotzu, van Wolferen, Monique E., Kruitwagen, Hedwig S., Oosterhoff, Loes A., Penning, Louis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958483/
https://www.ncbi.nlm.nih.gov/pubmed/31574998
http://dx.doi.org/10.3390/vetsci6040078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958483/
https://www.ncbi.nlm.nih.gov/pubmed/31574998
http://dx.doi.org/10.3390/vetsci6040078

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