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Reduced FXR Target Gene Expression in Copper-Laden Livers of COMMD1-Deficient Dogs
Wilson’s disease (WD), an autosomal recessive disorder, results in copper accumulation in the liver as a consequence of mutations in the gene ATPase copper transporting beta (ATP7B). The disease is characterized by chronic hepatitis, eventually resulting in liver cirrhosis. Recent studies have shown...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958483/ https://www.ncbi.nlm.nih.gov/pubmed/31574998 http://dx.doi.org/10.3390/vetsci6040078 |