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Small RNA Species and microRNA Profiles are Altered in Severe Asthma Nanovesicles from Broncho Alveolar Lavage and Associate with Impaired Lung Function and Inflammation

MicroRNAs are known to regulate important pathways in asthma pathology including the IL-6 and IFN pathways. MicroRNAs have been found not only within cells but also within extracellular vesicles such as exosomes. In this study, we particularly focused on microRNA cargo of nanovesicles in bronchoalve...

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Detalles Bibliográficos
Autores principales: Francisco-Garcia, Ana S., Garrido-Martín, Eva M., Rupani, Hitasha, Lau, Laurie C. K., Martinez-Nunez, Rocio T., Howarth, Peter H., Sanchez-Elsner, Tilman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958500/
https://www.ncbi.nlm.nih.gov/pubmed/31684064
http://dx.doi.org/10.3390/ncrna5040051