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Nintedanib and Sildenafil in Patients with Idiopathic Pulmonary Fibrosis and Right Heart Dysfunction. A Prespecified Subgroup Analysis of a Double-Blind Randomized Clinical Trial (INSTAGE)

Rationale: In the INSTAGE trial in patients with idiopathic pulmonary fibrosis (IPF) and severely impaired gas exchange, nintedanib plus sildenafil was associated with numerical benefits on St. George’s Respiratory Questionnaire (SGRQ) total score, brain natriuretic peptide (BNP), and FVC decline ve...

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Detalles Bibliográficos
Autores principales: Behr, Jürgen, Kolb, Martin, Song, Jin Woo, Luppi, Fabrizio, Schinzel, Birgit, Stowasser, Susanne, Quaresma, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958532/
https://www.ncbi.nlm.nih.gov/pubmed/31365829
http://dx.doi.org/10.1164/rccm.201903-0488OC