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C3a-C3aR signaling promotes breast cancer lung metastasis via modulating carcinoma associated fibroblasts

BACKGROUND: Mounting evidence suggests that complement components promote tumor progression via modulating immune suppression, angiogenesis, or tumor cell proliferation. However, the role of C3a-C3aR signaling in regulating lung metastasis of breast cancer remains unknown. METHODS: We performed vari...

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Detalles Bibliográficos
Autores principales: Shu, Chi, Zha, Haoran, Long, Haixia, Wang, Xinxin, Yang, Fei, Gao, Jianbao, Hu, Chunyan, Zhou, Li, Guo, Bo, Zhu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958674/
https://www.ncbi.nlm.nih.gov/pubmed/31931851
http://dx.doi.org/10.1186/s13046-019-1515-2