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KDM4B facilitates colorectal cancer growth and glucose metabolism by stimulating TRAF6-mediated AKT activation

BACKGROUND: Histone lysine demethylase 4B (KDM4B) has been implicated in various pathological processes and human diseases. Glucose metabolism is the main pattern of energy supply in cells and its dysfunction is closely related to tumorigenesis. Recent study shows that KDM4B protects against obesity...

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Detalles Bibliográficos
Autores principales: Li, Haijie, Lan, Jingqin, Wang, Guihua, Guo, Kaixuan, Han, Caishun, Li, Xiaolan, Hu, Junbo, Cao, Zhixin, Luo, Xuelai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958723/
https://www.ncbi.nlm.nih.gov/pubmed/31931846
http://dx.doi.org/10.1186/s13046-020-1522-3