ZDHXB-101 (3′,5-Diallyl-2, 4′-dihydroxy-[1,1′-biphen-yl]-3,5′-dicarbaldehyde) protects against airway remodeling and hyperresponsiveness via inhibiting both the activation of the mitogen-activated protein kinase and the signal transducer and activator of transcription-3 signaling pathways

Airway remodeling consists of the structural changes of airway walls, which is often considered the result of longstanding airway inflammation, but it may be present to an equivalent degree in the airways of children with asthma, raising the need for early and specific therapeutic interventions. The...

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Detalles Bibliográficos
Autores principales: Jiang, Jun-xia, Shen, Hui-juan, Guan, Yan, Jia, Yong-liang, Shen, Jian, Liu, Qi, Xie, Qiang-min, Yan, Xiao-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958776/
https://www.ncbi.nlm.nih.gov/pubmed/31931796
http://dx.doi.org/10.1186/s12931-020-1281-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958776/
https://www.ncbi.nlm.nih.gov/pubmed/31931796
http://dx.doi.org/10.1186/s12931-020-1281-x

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