Cargando…

Reduced chronic restraint stress in mice overexpressing hyperactive proteasomes in the forebrain

While chronic restraint stress (CRS) results in depression-like behaviors possibly through oxidative stress in the brain, its molecular etiology and the development of therapeutic strategies remain elusive. Since oxidized proteins can be targeted by the ubiquitin-proteasome system, we investigated w...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Ji Hyeon, Kim, Ahbin, Yun, Yejin, Park, Seoyoung, Lee, Jung Hoon, Lee, Yong-Seok, Lee, Min Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958796/
https://www.ncbi.nlm.nih.gov/pubmed/31931843
http://dx.doi.org/10.1186/s13041-020-0548-y