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FGF14 Functions as a Tumor Suppressor through Inhibiting PI3K/AKT/mTOR Pathway in Colorectal Cancer

We identified that Fibroblast Growth Factor 14 (FGF14) was preferentially methylated in colorectal cancer (CRC). In this study, we aimed to investigate the epigenetic regulation, biological function and molecular mechanism of FGF14 in CRC. The expression of FGF14 in CRC cell lines, normal human colo...

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Detalles Bibliográficos
Autores principales: Su, Tianhong, Huang, Linlin, Zhang, Ning, Peng, Sui, Li, Xiaoxing, Wei, Guangyan, Zhai, Ertao, Zeng, Zhirong, Xu, Lixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959027/
https://www.ncbi.nlm.nih.gov/pubmed/31949485
http://dx.doi.org/10.7150/jca.36316