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Inhibition of Carbonyl Reductase 1 Enhances Metastasis of Head and Neck Squamous Cell Carcinoma through β-catenin-Mediated Epithelial-Mesenchymal Transition

Objective: Human carbonyl reductase 1 (CBR1) plays key roles in the regulation of oxidative stress and tumor progression. However, the detailed mechanism and clinical correlation between CBR1 and tumor progression in head and neck squamous cell carcinoma (HNSCC) is largely unexplored. This study wil...

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Detalles Bibliográficos
Autores principales: Yun, Miyong, Choi, Ae Jin, Woo, Seon Rang, Noh, Joo Kyung, Sung, Ji-Youn, Lee, Jung-Woo, Eun, Young-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959035/
https://www.ncbi.nlm.nih.gov/pubmed/31942176
http://dx.doi.org/10.7150/jca.34303