Cargando…

Inhibition of Carbonyl Reductase 1 Enhances Metastasis of Head and Neck Squamous Cell Carcinoma through β-catenin-Mediated Epithelial-Mesenchymal Transition

Objective: Human carbonyl reductase 1 (CBR1) plays key roles in the regulation of oxidative stress and tumor progression. However, the detailed mechanism and clinical correlation between CBR1 and tumor progression in head and neck squamous cell carcinoma (HNSCC) is largely unexplored. This study wil...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yun, Miyong, Choi, Ae Jin, Woo, Seon Rang, Noh, Joo Kyung, Sung, Ji-Youn, Lee, Jung-Woo, Eun, Young-Gyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959035/ https://www.ncbi.nlm.nih.gov/pubmed/31942176 http://dx.doi.org/10.7150/jca.34303

Ejemplares similares

Carbonyl reductase 1 is a new target to improve the effect of radiotherapy on head and neck squamous cell carcinoma
por: Yun, Miyong, et al.
Publicado: (2018)

Clinical significance of FAT1 gene mutation and mRNA expression in patients with head and neck squamous cell carcinoma
por: Kim, Su Il, et al.
Publicado: (2022)

Association between cancer stem cell gene expression signatures and prognosis in head and neck squamous cell carcinoma
por: Kim, Su Il, et al.
Publicado: (2022)

Epithelial-mesenchymal transition gene signature is associated with prognosis and tumor microenvironment in head and neck squamous cell carcinoma
por: Jung, Ah Ra, et al.
Publicado: (2020)

Gene signature for prediction of radiosensitivity in human papillomavirus-negative head and neck squamous cell carcinoma
por: Kim, Su Il, et al.
Publicado: (2020)

Gene signature predicting recurrence in oral squamous cell carcinoma is characterized by increased oxidative phosphorylation
por: Noh, Joo Kyung, et al.
Publicado: (2022)

Polymorphism of Methylenetetrahydrofolate Reductase (MTHFR) gene and risk of Head and Neck Squamous Cell Carcinoma
por: Rodrigues, Juliana Olsen, et al.
Publicado: (2015)

Decreased carbonyl reductase 1 expression promotes tumor growth via epithelial mesenchymal transition in uterine cervical squamous cell carcinomas
por: Nishimoto, Yuki, et al.
Publicado: (2018)

Clinical Significance of CUB and Sushi Multiple Domains 1 Inactivation in Head and Neck Squamous Cell Carcinoma
por: Jung, Ah Ra, et al.
Publicado: (2018)

FAM83A promotes proliferation and metastasis via Wnt/β-catenin signaling in head neck squamous cell carcinoma
por: Ji, Huan, et al.
Publicado: (2021)

Carbonyl reductase as a significant predictor of survival and lymph node metastasis in epithelial ovarian cancer
por: Umemoto, M, et al.
Publicado: (2001)

CD200 Induces Epithelial-to-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma via β-Catenin-Mediated Nuclear Translocation
por: Shin, Seung-Phil, et al.
Publicado: (2019)

Low carbonyl reductase 1 expression is associated with poor prognosis in patients with oral squamous cell carcinoma
por: Yamanouchi, Ryota, et al.
Publicado: (2018)

Targeting Wnt/Beta-Catenin Signaling in HPV-Positive Head and Neck Squamous Cell Carcinoma
por: Brkic, Faris F., et al.
Publicado: (2022)

Inhibition of beta-catenin shows therapeutic potential in head and neck squamous cell carcinoma in vitro
por: Maier, Tobias, et al.
Publicado: (2022)

Immuno-PET imaging based radioimmunotherapy in head and neck squamous cell carcinoma model
por: Song, In Ho, et al.
Publicado: (2017)

Structural Basis for Substrate Specificity in Human Monomeric Carbonyl Reductases
por: Pilka, Ewa S., et al.
Publicado: (2009)

Clinico-Pathological Correlation of β-Catenin and Telomere Dysfunction in Head and Neck Squamous Cell Carcinoma Patients
por: Padhi, Swatishree, et al.
Publicado: (2015)

β-CATENIN is a positive prognostic marker for HPV-positive head and neck squamous cell carcinoma
por: Stoiber, Stefan, et al.
Publicado: (2023)

The Role of MicroRNAs in Recurrence and Metastasis of Head and Neck Squamous Cell Carcinoma
por: Yang, Chris X., et al.
Publicado: (2019)

Tumor Biomarkers for the Prediction of Distant Metastasis in Head and Neck Squamous Cell Carcinoma
por: Alfieri, Salvatore, et al.
Publicado: (2020)

Definitive local therapy to head and neck squamous cell carcinoma with distant metastasis
por: Borson, Steven, et al.
Publicado: (2022)

Clinicopathological Parameters Predicting Nodal Metastasis in Head and Neck Squamous Cell Carcinoma
por: Hashmi, Atif A, et al.
Publicado: (2023)

Epithelial-to-Mesenchymal Transition-Derived Heterogeneity in Head and Neck Squamous Cell Carcinomas
por: Baumeister, Philipp, et al.
Publicado: (2021)

The Clinicopathological Significance of Epithelial Mesenchymal Transition Associated Protein Expression in Head and Neck Squamous Cell Carcinoma
por: Kim, Kyu Ho, et al.
Publicado: (2014)

p70S6K promotes IL-6-induced epithelial-mesenchymal transition and metastasis of head and neck squamous cell carcinoma
por: Wu, Dandan, et al.
Publicado: (2016)

Discovery of New Carbonyl Reductases Using Functional Metagenomics and Applications in Biocatalysis
por: Newgas, Sophie A., et al.
Publicado: (2021)

Yes-Associated Protein Expression in Head and Neck Squamous Cell Carcinoma Nodal Metastasis
por: Ge, Lin, et al.
Publicado: (2011)

Fascin upregulation in primary head and neck squamous cell carcinoma is associated with lymphatic metastasis
por: PAPASPYROU, KONSTANTINOS, et al.
Publicado: (2014)

Overexpression of neuromedin U is correlated with regional metastasis of head and neck squamous cell carcinoma
por: Wang, Lei, et al.
Publicado: (2016)

Colon mass: a rare site of metastasis for squamous cell cancer of the head and neck
por: Greenberg, Shannon, et al.
Publicado: (2020)

Epithelial–Mesenchymal Transition Associated with Head and Neck Squamous Cell Carcinomas: A Review
por: González-González, Rogelio, et al.
Publicado: (2021)

Risk Factors and Survival Outcomes for Patients With Anastomotic Leakage After Surgery for Head and Neck Squamous Cell Carcinoma
por: Kim, Do-Youn, et al.
Publicado: (2014)

RNA-Seq Approach for Genetic Improvement of Meat Quality in Pig and Evolutionary Insight into the Substrate Specificity of Animal Carbonyl Reductases
por: Jung, Won Yong, et al.
Publicado: (2012)

Squamous cell carcinoma of head and neck: what internists should know
por: Jung, Kyungsuk, et al.
Publicado: (2020)

Prevalence of high-risk human papillomavirus and its genotype distribution in head and neck squamous cell carcinomas
por: Kim, Yuil, et al.
Publicado: (2020)

Growth Inhibitory Effect of Palatine Tonsil-derived Mesenchymal Stem Cells on Head and Neck Squamous Cell Carcinoma Cells
por: Lim, Yun-Sung, et al.
Publicado: (2012)

Long noncoding RNA MYOSLID promotes invasion and metastasis by modulating the partial epithelial-mesenchymal transition program in head and neck squamous cell carcinoma
por: Xiong, Hong-Gang, et al.
Publicado: (2019)

CEACAM5 inhibits the lymphatic metastasis of head and neck squamous cell carcinoma by regulating epithelial–mesenchymal transition via inhibiting MDM2
por: Wang, Xudong, et al.
Publicado: (2022)

Immunotherapy in head and neck squamous cell carcinoma and rare head and neck malignancies
por: Cavalieri, Stefano, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5q8e4vftkbv8iroa9p859acl0q