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Hyperactivation of IL-6/STAT3 pathway leaded to the poor prognosis of post-TACE HCCs by HIF-1α/SNAI1 axis-induced epithelial to mesenchymal transition

Transarterial chemoembolization (TACE) has been considered the standard treatment for intermediate-stage hepatocellular carcinoma according to BCLC algorithm. However, it has been unclear about the TACE-related predictive bio-markers and underlying molecular mechanisms. This investigation revealed t...

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Detalles Bibliográficos
Autores principales: Gai, Xiaohong, Zhou, Peng, Xu, Meng, Liu, Zhikui, Zheng, Xin, Liu, Qingguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959052/
https://www.ncbi.nlm.nih.gov/pubmed/31942180
http://dx.doi.org/10.7150/jca.35631