JNK/AP1 Pathway Regulates MYC Expression and BCR Signaling through Ig Enhancers in Burkitt Lymphoma Cells

In Burkitt lymphoma (BL), a chromosomal translocation by which the MYC gene is fused to an immunoglobulin (Ig) gene locus is frequently found. The translocated MYC gene is overexpressed, which is the major driver of BL tumorigenesis. Studies have shown that Ig enhancers are essential for MYC overexp...

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Detalles Bibliográficos
Autores principales: Ding, Xiaoling, Wang, Xiaoying, Zhu, Xueting, Zhang, Jie, Zhu, Yiqing, Shao, Xiaoyi, Zhou, Xiaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959055/
https://www.ncbi.nlm.nih.gov/pubmed/31942184
http://dx.doi.org/10.7150/jca.34055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959055/
https://www.ncbi.nlm.nih.gov/pubmed/31942184
http://dx.doi.org/10.7150/jca.34055

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