Effects of cholesterol content on activity of P-glycoproteins and membrane physical state, and consequences for anthelmintic resistance in the nematode Haemonchus contortus

Eukaryote plasma membranes protect cells from chemical attack. Xenobiotics, taken up through passive diffusion, accumulate in the membranes, where they are captured by transporters, among which P-glycoproteins (Pgps). In nematodes such as Haemonchus contortus, eggshells and cuticles provide addition...

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Detalles Bibliográficos
Autores principales: Riou, Mickaël, Guégnard, Fabrice, Le Vern, Yves, Grasseau, Isabelle, Koch, Christine, Blesbois, Elisabeth, Kerboeuf, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDP Sciences 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959138/
https://www.ncbi.nlm.nih.gov/pubmed/31934848
http://dx.doi.org/10.1051/parasite/2019079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959138/
https://www.ncbi.nlm.nih.gov/pubmed/31934848
http://dx.doi.org/10.1051/parasite/2019079

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