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Sesamin, a Naturally Occurring Lignan, Inhibits Ligand-Induced Lipogenesis through Interaction with Liver X Receptor Alpha (LXRα) and Pregnane X Receptor (PXR)

Liver X receptor (LXR) is a nuclear receptor that regulates various biological processes, including de novo lipogenesis, cholesterol metabolism, and inflammation. Selective inhibition of LXR may aid the treatment of nonalcoholic fatty liver disease (NAFLD). Sesamin is a naturally occurring lignan in...

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Detalles Bibliográficos
Autores principales: Tai, Tsai-Sung, Tien, Ni, Shen, Hsin-Yi, Chu, Fang-Yi, Wang, Charles C. N., Lu, Chieh-Hsiang, Yu, Hui-I, Kung, Fang-Ping, Chuang, Hsiang-Hsun, Lee, Ying-Ray, Chang, Hsiao-Yun, Lim, Yun-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959160/
https://www.ncbi.nlm.nih.gov/pubmed/31976003
http://dx.doi.org/10.1155/2019/9401648