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Sesamin, a Naturally Occurring Lignan, Inhibits Ligand-Induced Lipogenesis through Interaction with Liver X Receptor Alpha (LXRα) and Pregnane X Receptor (PXR)
Liver X receptor (LXR) is a nuclear receptor that regulates various biological processes, including de novo lipogenesis, cholesterol metabolism, and inflammation. Selective inhibition of LXR may aid the treatment of nonalcoholic fatty liver disease (NAFLD). Sesamin is a naturally occurring lignan in...
Autores principales: | Tai, Tsai-Sung, Tien, Ni, Shen, Hsin-Yi, Chu, Fang-Yi, Wang, Charles C. N., Lu, Chieh-Hsiang, Yu, Hui-I, Kung, Fang-Ping, Chuang, Hsiang-Hsun, Lee, Ying-Ray, Chang, Hsiao-Yun, Lim, Yun-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959160/ https://www.ncbi.nlm.nih.gov/pubmed/31976003 http://dx.doi.org/10.1155/2019/9401648 |
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