Genetic disarray follows mutant KLF1-E325K expression in a congenital dyserythropoietic anemia patient
Congenital dyserythropoietic anemia type IV is caused by a heterozygous mutation, Glu325Lys (E325K), in the KLF1 transcription factor. Molecular characteristics of this disease have not been clarified, partly due to its rarity. We expanded erythroid cells from a patient’s peripheral blood and analyz...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959163/ https://www.ncbi.nlm.nih.gov/pubmed/30872368 http://dx.doi.org/10.3324/haematol.2018.209858 |