Platelet HIF-2α promotes thrombogenicity through PAI-1 synthesis and extracellular vesicle release

Oxygen-compromised environments, such as high altitude, are associated with platelet hyperactivity. Platelets confined within the relatively impervious core of an aggregate/thrombus have restricted access to oxygen, yet they continue to perform energy-intensive procoagulant activities that sustain t...

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Detalles Bibliográficos
Autores principales: Chaurasia, Susheel N., Kushwaha, Geeta, Kulkarni, Paresh P., Mallick, Ram L., Latheef, Nazmy A., Mishra, Jai K., Dash, Debabrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959171/
https://www.ncbi.nlm.nih.gov/pubmed/31004026
http://dx.doi.org/10.3324/haematol.2019.217463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959171/
https://www.ncbi.nlm.nih.gov/pubmed/31004026
http://dx.doi.org/10.3324/haematol.2019.217463

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