Relevance of platelet desialylation and thrombocytopenia in type 2B von Willebrand disease: preclinical and clinical evidence

Patients with type 2B von Willebrand disease (vWD) (caused by gain-of-function mutations in the gene coding for von Willebrand factor) display bleeding to a variable extent and, in some cases, thrombocytopenia. There are several underlying causes of thrombocytopenia in type 2B vWD. It was recently s...

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Detalles Bibliográficos
Autores principales: Dupont, Annabelle, Soukaseum, Christelle, Cheptou, Mathilde, Adam, Frédéric, Nipoti, Thomas, Lourenco-Rodrigues, Marc-Damien, Legendre, Paulette, Proulle, Valérie, Rauch, Antoine, Kawecki, Charlotte, Bryckaert, Marijke, Rosa, Jean-Philippe, Paris, Camille, Ternisien, Catherine, Boisseau, Pierre, Goudemand, Jenny, Borgel, Delphine, Lasne, Dominique, Maurice, Pascal, Lenting, Peter J., Denis, Cécile V., Susen, Sophie, Kauskot, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959185/
https://www.ncbi.nlm.nih.gov/pubmed/30819911
http://dx.doi.org/10.3324/haematol.2018.206250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959185/
https://www.ncbi.nlm.nih.gov/pubmed/30819911
http://dx.doi.org/10.3324/haematol.2018.206250

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