Challenges in reporting pathogenic/potentially pathogenic variants in 94 cancer predisposing genes - in pediatric patients screened with NGS panels

The benefit of reporting unsolicited findings in Next Generation Sequencing (NGS) related to cancer genes in children may have implications for family members, nevertheless, could also cause distress. We aimed to retrospectively investigate germline variants in 94 genes implicated in oncogenesis, in...

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Detalles Bibliográficos
Autores principales: Chirita-Emandi, Adela, Andreescu, Nicoleta, Zimbru, Cristian G., Tutac, Paul, Arghirescu, Smaranda, Serban, Margit, Puiu, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959212/
https://www.ncbi.nlm.nih.gov/pubmed/31937788
http://dx.doi.org/10.1038/s41598-019-57080-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959212/
https://www.ncbi.nlm.nih.gov/pubmed/31937788
http://dx.doi.org/10.1038/s41598-019-57080-9

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