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The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness

Neuroblastoma is an aggressive childhood cancer arising from sympatho-adrenergic neuronal progenitors. The low survival rates for high-risk disease point to an urgent need for novel targeted therapeutic approaches. Detailed molecular characterization of the neuroblastoma genomic landscape indicates...

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Detalles Bibliográficos
Autores principales: Mus, Liselot M., Lambertz, Irina, Claeys, Shana, Kumps, Candy, Van Loocke, Wouter, Van Neste, Christophe, Umapathy, Ganesh, Vaapil, Marica, Bartenhagen, Christoph, Laureys, Genevieve, De Wever, Olivier, Bexell, Daniel, Fischer, Matthias, Hallberg, Bengt, Schulte, Johannes, De Wilde, Bram, Durinck, Kaat, Denecker, Geertrui, De Preter, Katleen, Speleman, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959226/
https://www.ncbi.nlm.nih.gov/pubmed/31937834
http://dx.doi.org/10.1038/s41598-019-57076-5