Efficient generation of thymic epithelium from induced pluripotent stem cells that prolongs allograft survival

The thymus plays a significant role in establishing immunological self-tolerance. Previous studies have revealed that host immune reaction to allogeneic transplants could be regulated by thymus transplantation. However, physiological thymus involution hinders the clinical application of these insigh...

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Detalles Bibliográficos
Autores principales: Otsuka, Ryo, Wada, Haruka, Tsuji, Hyuma, Sasaki, Airi, Murata, Tomoki, Itoh, Mizuho, Baghdadi, Muhammad, Seino, Ken-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959230/
https://www.ncbi.nlm.nih.gov/pubmed/31937817
http://dx.doi.org/10.1038/s41598-019-57088-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959230/
https://www.ncbi.nlm.nih.gov/pubmed/31937817
http://dx.doi.org/10.1038/s41598-019-57088-1

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