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Efficient generation of thymic epithelium from induced pluripotent stem cells that prolongs allograft survival
The thymus plays a significant role in establishing immunological self-tolerance. Previous studies have revealed that host immune reaction to allogeneic transplants could be regulated by thymus transplantation. However, physiological thymus involution hinders the clinical application of these insigh...
Autores principales: | Otsuka, Ryo, Wada, Haruka, Tsuji, Hyuma, Sasaki, Airi, Murata, Tomoki, Itoh, Mizuho, Baghdadi, Muhammad, Seino, Ken-ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959230/ https://www.ncbi.nlm.nih.gov/pubmed/31937817 http://dx.doi.org/10.1038/s41598-019-57088-1 |
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