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Impact of BH3-mimetics on Human and Mouse Blood Leukocytes: A Comparative Study

BH3-mimetics are small molecule inhibitors that neutralize the function of anti-apoptotic BCL-2 family members. BH3-mimetics have recently gained a lot of popularity in oncology because of their success in cancer treatment. However, BH3-mimetics might have a broader clinical application. Here, we es...

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Detalles Bibliográficos
Autores principales: Rohner, Lionel, Reinhart, Ramona, Iype, Joseena, Bachmann, Sofia, Kaufmann, Thomas, Fux, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959258/
https://www.ncbi.nlm.nih.gov/pubmed/31937836
http://dx.doi.org/10.1038/s41598-019-57000-x