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Domain-mediated interactions for protein subfamily identification

Within a protein family, proteins with the same domain often exhibit different cellular functions, despite the shared evolutionary history and molecular function of the domain. We hypothesized that domain-mediated interactions (DMIs) may categorize a protein family into subfamilies because the diver...

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Detalles Bibliográficos
Autores principales: Lee, Heetak, Kim, Inhae, Han, Seong Kyu, Kim, Donghyo, Kong, Jungho, Kim, Sanguk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959277/
https://www.ncbi.nlm.nih.gov/pubmed/31937869
http://dx.doi.org/10.1038/s41598-019-57187-z