Extracellular Superoxide Dismutase Regulates Early Vascular Hyaluronan Remodeling in Hypoxic Pulmonary Hypertension

Chronic hypoxia leads to pathologic remodeling of the pulmonary vasculature and pulmonary hypertension (PH). The antioxidant enzyme extracellular superoxide dismutase (SOD3) protects against hypoxia-induced PH. Hyaluronan (HA), a ubiquitous glycosaminoglycan of the lung extracellular matrix, is rapi...

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Detalles Bibliográficos
Autores principales: Tseng, Victor, Ni, Kevin, Allawzi, Ayed, Prohaska, Clare, Hernandez-Lagunas, Laura, Elajaili, Hanan, Cali, Valbona, Midura, Ronald, Hascall, Vincent, Triggs-Raine, Barbara, Petrache, Irina, Hart, C. Michael, Nozik-Grayck, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959284/
https://www.ncbi.nlm.nih.gov/pubmed/31937874
http://dx.doi.org/10.1038/s41598-019-57147-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959284/
https://www.ncbi.nlm.nih.gov/pubmed/31937874
http://dx.doi.org/10.1038/s41598-019-57147-7

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