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Proteinase K resistant cores of prions and amyloids

Amyloids and their infectious subset, prions, represent fibrillary aggregates with regular structure. They are formed by proteins that are soluble in their normal state. In amyloid form, all or part of the polypeptide sequence of the protein is resistant to treatment with proteinase K (PK). Amyloids...

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Detalles Bibliográficos
Autores principales: Kushnirov, Vitaly V., Dergalev, Alexander A., Alexandrov, Alexander I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959286/
https://www.ncbi.nlm.nih.gov/pubmed/31876447
http://dx.doi.org/10.1080/19336896.2019.1704612