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Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain
Paralleling the activation of dorsal horn microglia after peripheral nerve injury is a significant expansion and proliferation of macrophages around injured sensory neurons in dorsal root ganglia (DRG). Here we demonstrate a critical contribution of DRG macrophages, but not those at the nerve injury...
Autores principales: | Yu, Xiaobing, Liu, Hongju, Hamel, Katherine A., Morvan, Maelig G., Yu, Stephen, Leff, Jacqueline, Guan, Zhonghui, Braz, Joao M., Basbaum, Allan I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959328/ https://www.ncbi.nlm.nih.gov/pubmed/31937758 http://dx.doi.org/10.1038/s41467-019-13839-2 |
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