Bright ligand-activatable fluorescent protein for high-quality multicolor live-cell super-resolution microscopy

We introduce UnaG as a green-to-dark photoswitching fluorescent protein capable of high-quality super-resolution imaging with photon numbers equivalent to the brightest photoswitchable red protein. UnaG only fluoresces upon binding of a fluorogenic metabolite, bilirubin, enabling UV-free reversible...

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Detalles Bibliográficos
Autores principales: Kwon, Jiwoong, Park, Jong-Seok, Kang, Minsu, Choi, Soobin, Park, Jumi, Kim, Gyeong Tae, Lee, Changwook, Cha, Sangwon, Rhee, Hyun-Woo, Shim, Sang-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959352/
https://www.ncbi.nlm.nih.gov/pubmed/31937765
http://dx.doi.org/10.1038/s41467-019-14067-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959352/
https://www.ncbi.nlm.nih.gov/pubmed/31937765
http://dx.doi.org/10.1038/s41467-019-14067-4

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