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Endogenous and exogenous glucocorticoids abolish the efficacy of immune-dependent cancer therapies

Glucocorticoids mediate potent anti-inflammatory and immunosuppressive effects. A chronic elevation of the endogenous glucocorticoid tonus subsequent to mental stress, as well as continuous treatment with exogenous glucocorticoids, activate an immunosuppressive transcription factor, TSC22D3, in dend...

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Detalles Bibliográficos
Autores principales: Ma, Yuting, Yang, Heng, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959448/
https://www.ncbi.nlm.nih.gov/pubmed/32002285
http://dx.doi.org/10.1080/2162402X.2019.1673635