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Endogenous and exogenous glucocorticoids abolish the efficacy of immune-dependent cancer therapies
Glucocorticoids mediate potent anti-inflammatory and immunosuppressive effects. A chronic elevation of the endogenous glucocorticoid tonus subsequent to mental stress, as well as continuous treatment with exogenous glucocorticoids, activate an immunosuppressive transcription factor, TSC22D3, in dend...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959448/ https://www.ncbi.nlm.nih.gov/pubmed/32002285 http://dx.doi.org/10.1080/2162402X.2019.1673635 |