Secreted calreticulin mutants subvert anticancer immunosurveillance

Mutations of the gene coding for calreticulin (CALR) that cause the loss of the C-terminal KDEL motif abolish its retention in the endoplasmic reticulum and cause CALR to be secreted from cells. Specific CALR mutants bearing a novel C-terminus can precipitate the manifestation of myeloproliferative...

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Detalles Bibliográficos
Autores principales: Liu, Peng, Zhao, Liwei, Kroemer, Guido, Kepp, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959454/
https://www.ncbi.nlm.nih.gov/pubmed/32002304
http://dx.doi.org/10.1080/2162402X.2019.1708126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959454/
https://www.ncbi.nlm.nih.gov/pubmed/32002304
http://dx.doi.org/10.1080/2162402X.2019.1708126

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