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Identification and validation of mRNA 3′untranslated regions of DNMT3B and TET3 as novel competing endogenous RNAs of the tumor suppressor PTEN

PTEN inactivation is a frequent event in oncogenesis. Multiple regulatory mechanisms such as promoter hypermethylation, antisense regulation, histone modifications, targeting by microRNAs (miRNAs/miRs) and regulation by transcription factors have all been shown to affect the tumor suppressor functio...

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Detalles Bibliográficos
Autores principales: Roquid, Kenneth Anthony R., Alcantara, Krizelle Mae M., Garcia, Reynaldo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959461/
https://www.ncbi.nlm.nih.gov/pubmed/31894272
http://dx.doi.org/10.3892/ijo.2019.4947