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Identification and validation of mRNA 3′untranslated regions of DNMT3B and TET3 as novel competing endogenous RNAs of the tumor suppressor PTEN
PTEN inactivation is a frequent event in oncogenesis. Multiple regulatory mechanisms such as promoter hypermethylation, antisense regulation, histone modifications, targeting by microRNAs (miRNAs/miRs) and regulation by transcription factors have all been shown to affect the tumor suppressor functio...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959461/ https://www.ncbi.nlm.nih.gov/pubmed/31894272 http://dx.doi.org/10.3892/ijo.2019.4947 |