Inhibition of PIM2 in liver cancer decreases tumor cell proliferation in vitro and in vivo primarily through the modulation of cell cycle progression

Liver cancer is the fourth leading cause of cancer-related mortality worldwide with limited therapeutic options. Thus, novel treatment strategies are urgently required. While the oncogenic kinase, proviral integration site for Moloney murine leukemia virus 2 (PIM2), has been shown to be overexpresse...

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Detalles Bibliográficos
Autores principales: Kronschnabl, Pia, Grünweller, Arnold, Hartmann, Roland K., Aigner, Achim, Weirauch, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959465/
https://www.ncbi.nlm.nih.gov/pubmed/31894300
http://dx.doi.org/10.3892/ijo.2019.4936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959465/
https://www.ncbi.nlm.nih.gov/pubmed/31894300
http://dx.doi.org/10.3892/ijo.2019.4936

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