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Non-redundant roles in sister chromatid cohesion of the DNA helicase DDX11 and the SMC3 acetyl transferases ESCO1 and ESCO2

In a process linked to DNA replication, duplicated chromosomes are entrapped in large, circular cohesin complexes and functional sister chromatid cohesion (SCC) is established by acetylation of the SMC3 cohesin subunit. Roberts Syndrome (RBS) and Warsaw Breakage Syndrome (WABS) are rare human develo...

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Detalles Bibliográficos
Autores principales: Faramarz, Atiq, Balk, Jesper A., van Schie, Janne J. M., Oostra, Anneke B., Ghandour, Cherien A., Rooimans, Martin A., Wolthuis, Rob M. F., de Lange, Job
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959578/
https://www.ncbi.nlm.nih.gov/pubmed/31935221
http://dx.doi.org/10.1371/journal.pone.0220348