OGG1 deficiency alters the intestinal microbiome and increases intestinal inflammation in a mouse model

OGG1-deficient (Ogg1(-/-)) animals display increased propensity to age-induced and diet-induced metabolic diseases, including insulin resistance and fatty liver. Since the intestinal microbiome is increasingly understood to play a role in modulating host metabolic responses, we examined gut microbia...

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Detalles Bibliográficos
Autores principales: Simon, Holly, Vartanian, Vladimir, Wong, Melissa H., Nakabeppu, Yusaku, Sharma, Priyanka, Lloyd, R. Stephen, Sampath, Harini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959583/
https://www.ncbi.nlm.nih.gov/pubmed/31935236
http://dx.doi.org/10.1371/journal.pone.0227501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959583/
https://www.ncbi.nlm.nih.gov/pubmed/31935236
http://dx.doi.org/10.1371/journal.pone.0227501

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