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Improving patient classification and biomarker assessment using Gaussian Mixture Models and Bayes’ rule
In clinical research, determining cutoff values for continuous variables in test results remains challenging, particularly when considering candidate biomarkers or therapeutic targets for disease. Distribution of a continuous variable into two populations is known as dichotomization and has been com...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959929/ https://www.ncbi.nlm.nih.gov/pubmed/31984216 http://dx.doi.org/10.18632/oncoscience.494 |