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In vitro reconstitution of branching microtubule nucleation

Eukaryotic cell division requires the mitotic spindle, a microtubule (MT)-based structure which accurately aligns and segregates duplicated chromosomes. The dynamics of spindle formation are determined primarily by correctly localising the MT nucleator, γ-Tubulin Ring Complex (γ-TuRC), within the ce...

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Detalles Bibliográficos
Autores principales: Tariq, Ammarah, Green, Lucy, Jeynes, J Charles G, Soeller, Christian, Wakefield, James G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959987/
https://www.ncbi.nlm.nih.gov/pubmed/31933481
http://dx.doi.org/10.7554/eLife.49769