Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions

Human cytomegalovirus (HCMV) extensively modulates host cells, downregulating >900 human proteins during viral replication and degrading ≥133 proteins shortly after infection. The mechanism of degradation of most host proteins remains unresolved, and the functions of many viral proteins are incom...

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Detalles Bibliográficos
Autores principales: Nobre, Luis V, Nightingale, Katie, Ravenhill, Benjamin J, Antrobus, Robin, Soday, Lior, Nichols, Jenna, Davies, James A, Seirafian, Sepehr, Wang, Eddie CY, Davison, Andrew J, Wilkinson, Gavin WG, Stanton, Richard J, Huttlin, Edward L, Weekes, Michael P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959991/
https://www.ncbi.nlm.nih.gov/pubmed/31873071
http://dx.doi.org/10.7554/eLife.49894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959991/
https://www.ncbi.nlm.nih.gov/pubmed/31873071
http://dx.doi.org/10.7554/eLife.49894

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